Powder pigment vs acrylic pre dispersed ink

Hey all, Hoping to start a discussion about the differences between these kinds of inks, pros and cons, personal experiences etc etc. Having used both I will say I’ve had an easier time by and large saturating color with most eternal ink products, but have heard negative things about acrylics lasting power and it’s potential to be harmful and cause allergic reactions. Just curious if anyone had an opinion and wanted to weigh in!