First Dose of Ozempic and Emotional Side Effects – Need Advice

Hi everyone,

I took my first dose of Ozempic (0.25mg) three days ago, and unfortunately, I experienced some intense emotional side effects the next day. I felt deeply depressed, like nothing brought me joy anymore. I was emotionally numb, felt physically unwell, and was overwhelmed with sadness.

On top of that, I started feeling anxious, which eventually led me to take a benzo to calm myself down. Thankfully, I’m feeling much better today.

For some context, I have ADHD and have been on Zoloft for 8 years. I’m taking Ozempic to address my severe obesity. My doctor told me that if the depressive symptoms are indeed caused by the medication, I should stop taking it.

This is incredibly frustrating for me because I finally felt hopeful about tackling my weight issues, and now I’m worried that this might not work out.

My question is: does this sound like a sign that I might not tolerate the medication well? Or could this just be an initial side effect that might subside with time? Has anyone else experienced something similar?

I’d really appreciate hearing about your experiences or any advice you might have!

Thanks so much!

Edit: I'm much better and I will continue taking it. It was the first response only. Thanks for all the replies.