Gallbladder and MTHFR
I am compound heterozygous 1298 and 6667 and after our 4th baby (he's 7mos old and I'm breastfeeding ) started getting bilary colic pain and presumably acid reflux and gall bladder pain. I refused PPIs. It was/is bad enough that it is waking me up at night with pain and I was curled up in a ball on the floor and have been to the ER several times to address it as I was at a loss as to what to do. I met with a GI who completed an upper endoscopy (no stomach ulcers/no h.pylori), colonoscopy (clear health) and HIDA scan (gallbladder functioning at 71%). Ended up taking antibiotics for a random ear infection and no more waking up at night writhing in pain for about 3 months. More recently it started coming back and at this point I have no appetite because anytime I eat I get an episode, have constant pain /ache on my right side which then radiates to either 2 inches above my belly button or right under my breastbone and it is CONSTANT and I often feel throbbing / my artery about 2 inches above my belly button. Plus stool is white with constipation. I can't sleep, can't eat and have no idea what to do other than remove my gallbladder and consider it a loss hoping that is what will give me my life back. During this round of diagnostic I also found a resurgence of Bacterial vaginosis by which prompted me to start metronidazole although it A)doesn't seem to be working and B) has started to cause what I believe hearing loss in one ear so I am discontinuing immediately. Any advice 😬 I presume at this point I am slow COMT and possibly have histamine problems but I need to address my gallbladder as a priority before genetic testing as I literally am not sleeping well and I have 4 young children two of which have special needs so I am at a complete loss 😵💫 My plan after figuring out the gallbladder issue is ordering a panel from stratagene or 23and me to import to genetic genie so I can get a better insight as to WTF is going on with my digestive system because this is unsustainable. Also I have been off of dairy and gluten and currently following low fodmap diet and drinking green tea and some aloe vera mostly but still have a gross metallic taste in my mouth. I was previously taking dessicated beef liver but have discontinued until I have a better idea of what is happening. I did start Choline and started taking Lipo gen by MetaGenics which has some taurine and magnesium. On the plus side I've lost 5ish lbs and it's really hard for me to lose weight 😅
TLDR; any advice for a functional practitioner familiar with MTHFR? Also cost/benefit of removing a suspected diseased or faulty gallbladder when I am not sleeping or able to eat anything without a bilary episode. 😵💫